Which step in the progression from healthy liver to hepatocellular carcinoma cannot be reversed? The Progression from Healthy Liver to Hepatocellular Carcinoma and its Irreversible Steps

The Development from Wholesome Liver to Hepatocellular Carcinoma and its Irreversible Steps

Hepatocellular carcinoma (HCC) is a kind of most cancers that originates within the liver. The development from a wholesome liver to HCC is a protracted and sophisticated course of that includes a number of steps. One in every of these steps is irreversible, which means it can’t be reversed. Step one within the development from a wholesome liver to HCC is irritation. That is brought on by continual liver illnesses, resembling hepatitis B or C, that trigger harm to liver cells over time. This harm can result in cirrhosis, a situation the place the liver turns into scarred and unable to perform correctly (Liu & Hsieh, 2019).
The second step is the event of precancerous lesions within the liver. These are irregular tissue growths and may be brought on by a number of elements resembling continual irritation and cirrhosis (Ribeiro et al., 2018). These lesions will also be brought on by genetic mutations, which is when the DNA of a cell is modified and may now not carry out its regular features.
The third step is the formation of a tumor. At this stage, the most cancers cells start to develop and divide, forming a tumor (Alhosin et al., 2020). That is the step within the development from a wholesome liver to HCC that can not be reversed. Cont….

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