After twelve days of fasting (gluconeogenesis is the primary process meeting glucose needs), are most insulin receptors occupied? Glucagon receptors? Please clearly explain what is occurring (within the liver hepatocyte) at the adenylyl cyclase enzyme. The Occupancy of Insulin and Glucagon Receptors after Twelve Days of Fasting

The Occupancy of Insulin and Glucagon Receptors after Twelve Days of Fasting

After twelve days of fasting, the first course of which meets the physique’s glucose wants is gluconeogenesis, a metabolic course of which is primarily chargeable for producing glucose from non-carbohydrate sources reminiscent of glycerol and lactate. On the similar time, there’s a lower within the physique’s insulin secretion and a rise in glucagon secretion, which permits the physique to entry its vitality shops. Due to this fact, after twelve days of fasting, most insulin receptors are prone to be occupied and glucagon receptors are additionally prone to be occupied. On the adenylyl cyclase enzyme, which is discovered within the liver hepatocyte, a hormone referred to as cAMP binds to the enzyme, prompting it to transform ATP to cAMP. cAMP then binds to the glucagon receptor, activating a course of which results in the conversion of glycogen to glucose, and the manufacturing of glucose by means of gluconeogenesis. As well as, cAMP additionally binds to the insulin receptor, permitting the physique to control glucose ranges and convert glucose to glycogen for vitality storage. Due to this fact, after twelve days of fasting, each insulin and glucagon receptors are prone to be occupied, permitting the physique to entry its vitality shops and keep glucose ranges. Cont…

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